Naeem Bokhari was born in Lahore at renown specialist Dr. Syed Altaf Hussain Bokhari house. Saleem Altaf Bokhari, a fast bowler for Pakistan, is his older brother. After earning his degree from Government College University in Lahore, he went on to study law.
On February 16, 2007, he released an open letter criticising Chief Justice Iftikhar Mohammed Chaudhry, which sparked debate. President Pervez Musharraf fired the Chief Justice as a result of this. After the scandal peaked on March 9, 2007, the Punjab Bar Council reacted and expelled him from the organisation. His membership was later extended.